CxPM Science

Cx Precision Medicine technology enables physicians at the primary care level to more accurately diagnose neurodegenerative disorders leading to earlier, targeted treatments for individual patients

A new approach for targeted intervention

Alzheimer’s and other neurodegenerative diseases are not one pathology or disease, but rather comprise many subgroups and sub-pathologies.

Just like one drug cannot treat every cancer patient, one drug or treatment plan cannot treat every patient afflicted with Alzheimer’s Disease, or any neurodegenerative disease, for that matter.

Sid O’Bryant, PhD
Executive Director, Institute for Translational Research
Dr. Joe & Peggy Schooler Endowed Chair in Pharmacology and Neuroscience
University of North Texas Health Science Center

NeuroFirst™ Tests are based on the extensive research and development led by Dr. Sid O'Bryant


CxPM's paradigm-changing technology

Our technology combines proteomics and machine learning.  We measure a large number of proteins in blood and then use sophisticated algorithms, trained on thousands of samples, to drive the results of our tests.

CxPM’s NeuroFirst products include:

NeuroFirst Memory Test:   Designed for patients over age 60 who are complaining of memory loss or have other suspected symptoms of Alzheimer’s Dementia. This test rules out Alzheimer’s Dementia.

NeuroFirst™ Parkinson’s Test:  Designed for patients over age 50 who are complaining of tremors or other movement  disorders.  This test rules out Parkinson’s Disease as the cause of the movement disorder.

All CxPM products are based on a proteomic approach to analyzing biomarkers

What are protein biomarkers?

A biomarker is a measurable indicator of a specific biological state or process within an organism (ie, Humans).

The four main classes are molecular, physiologic, histologic and radiographic biomarkers. All four types of biomarkers have a clinical role in narrowing or guiding treatment decisions and follow a sub-categorization of being either predictive, prognostic, or diagnostic.

Why are proteins good biomarkers?

They can reflect the state of cells at various stages of disease progression. Secreted proteins have an important role in cell to cell signaling, communication, and growth as they reflect the various stages of pathological conditions such as Alzheimer’s or Parkinson’s Disease.